Police spokesperson Assistant Commissioner Paul Nyathi confirmed the accident.
Asst Comm Nyathi said the accident occurred after the kombi, which was carrying 13 passengers, collided head-on with a lorry.
The deceased were taken to Marondera Provincial Hospital mortuary, while the injured were being treated at the same health centre.
Of the 13 injured, six were said to be in critical condition at Marondera Hospital.
Asst Comm Nyathi urged transport operators to comply with Covid-19 lockdown regulations as the kombi was not contracted to Zupco.